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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42b3b2baf0b4ee933d791590338f089597e0b3229f27adae6375859394ef52d' 
  AND token = 'VtCABAUG0O38H+vC4sJMyXKzTAzh3rArq2WUxM0L5dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}