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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6118078c62f55dc1c3e520d49a0a291b25076591ee030245f2b931900c2663fe' 
  AND token = 'ozqDInuzJf4dvGY9V5jQa4FyxkWxyveb4xUCf7qFXX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}