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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d10fe230e70b7f9a42a8ce72f9dd0b0e42534a6ad99969012bf5980f0f38d7' 
  AND token = 'qfogUqc5TdWj8q5ZhyrDWPrcM1vPgOsfiVGlcEc/22Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}