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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec37085bedfa50a78da6d7c23a40d6387fb18e3f72ee21f04633e92f405e126b' 
  AND token = 'xSPFfXypaZn/u3bbycF4/kbxb8ISWfir2dN6QQLXw88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}