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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '254f8894501f3f67e3ee681ff8e6a5db987670dc7fbd02b64c7059faa29ba54c' 
  AND token = 'vGx7cX/EPF7ubqcXF+L8OuwLo9v3CBbiv0QQ9KwyPeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}