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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f13c8cbecfcf9917d2044e6bd6c88f524a730cd295769bf490ee425e9269f4c5' 
  AND token = 'cpF0+F4YHhstM/4sMLdHzrbaS4vL1Lrf6de63B2Hqwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}