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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff04d423e49d914e811165f62815aeaf0f5aebc0f0aa01eacbbec8a98db85789' 
  AND token = 'VMC9f4Jz68hGIZplYJk4HYgy+MrFr2Nno+ekp8SKnbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}