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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a32ffc886f7b34401328c8efa7725e6ba0427102fc0d5ee4441c8e79cbc8e90' 
  AND token = 'M/0NbopykfHzVABNPaYFsgCKCHXvZ3ZP0skcOZtXA6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}