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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1d4824196cb1bc33f135e376197effb081c6a4276d74fe294276a999c99cb13' 
  AND token = '0kuLo6A8cMuUOHzNcm1RmWI/RVgIxCvvZDrh5tvcUZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}