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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44bb86987c09397d6744d238b37b8590bfc1e1407205df02823b8b715695fc5e' 
  AND token = 'IqNHwohPmXYIYdDX2zr3n93dHOmeJBD5lqtdyuIZC8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}