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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '402d3644658949ed3603ef3ab8826542b65841b608dfd35e72f7ac5790189355' 
  AND token = 'AYWUIH5uLDc3YJFtfTLjQW/RKORczNfiymK6SnR7wSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}