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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ff7e3f010d7e488bd6a872e6357a76f0e70147287102ae7ba0634f69cef239' 
  AND token = '1vyXYwgsfoF+tzkTSwwofz38brg+UH72vmgh7h9n6mE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}