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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e4c976bd5b8e0435009e94ffc6294f6ddb6f34f78c9098cd868f467d8fff19' 
  AND token = 'iHIG+kklwGg/059VQBhe7gb7fOPGMCTDRySgRR/oQgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}