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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '811e555e906a94472e2875bdd53acdfa2026dfa7156aa6cf04acb9daf0eb02c1' 
  AND token = 'Wp+p4mtKQWBm+/n3tW2RsawQn5K9bnjF5v3GHM8FAbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}