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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541de9b3313d6eb3797548eb1f65669cac5df43129dad4a3314bc95c5b681fcd' 
  AND token = '4DUfxp2abl1CA0ICAUJ4z5mPjYjEQxXm9jPZvLuoywo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}