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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69e2af4b633e8e43cb0b4c10a13b4dd07990bc70beeb65621a5986aac947706f' 
  AND token = 'lU/wJ5cKNg/xJ0Cr8/wl+b0UfBbOtAk6XYLiq6sNnQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}