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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38547a26228cd6efd9a2199a43d042571d8d2e89a3937e69645ced2844d1456' 
  AND token = 'ttoDYpEUr3Iz6jYxQR1Kd+91G7uzW3lSBxZPRZ0aQtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}