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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f335c71c5e37c7ba3b41df8ead7ee0811982e6f87d8920d613e820db82c38944' 
  AND token = 'EDdaCbYyWdg1OBy5I1bucCFjxM+v2gHpWc9QgSwUuwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}