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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2b2cf3722130402adf42ae2c4fe45613740f2eac03c2a31af285d3cf31169d' 
  AND token = 'bGdr6Q0WyJ4U3vhev2B3a/BVMOXNSyz4vbLt8yBW3x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}