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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b31c336c1f6a9eae64ac52b44d2cc843b827affeba101971154e4529e715043' 
  AND token = 'vezPpaFNOPuaUSZrhs/6cpRb+u12D058KvayKRkaiD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}