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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '955f9b0ba1a4283d8714e807dd287a9b40002193ab7853c9a5595074896a2f01' 
  AND token = 'EU+dJdmeUBUM9v385aGtLM32LN4TirULMWGg7WMP1CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}