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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1401c25ea092897e1c7c3cc211fd8a653903fcb541a9e8e841b2f7666990d81b' 
  AND token = 'n0AsAgUU0CIh8kO3J0fmmRgIpSl4/Tijhhx7cQ9NOzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}