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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab65d5ac7bfc5e4a6a7daedab67c6769e88a583b60d7549e32b6aab12c4ab25d' 
  AND token = '1tyqyw1ybR/lwisuh7U+GLKxNGVM+OkQVOtuRsRp0Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}