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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f9a41b6c8161eb57d0b3deb0d550b3ba33d64abbdc4a52460c73f16113983ec' 
  AND token = 'D4522eyEJbosOv3k8zM0lGSlTjKcMNP9UB6jaNhQ7Ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}