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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '014c8ccdc77e2fbbb095bdb80a148ac5d425e06a0e47499a86a249a1cda4e243' 
  AND token = '7xPrdcNimZ8P5KInktJRLHRnZnn5c1ww+8UlGSIIBFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}