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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b425773d71b4c3d9c70179f9189f2566a20a0ec34ed791ba3d2e79110f30ab' 
  AND token = 'pvAqJWpdn9JcRnbdTtPP3DXSqpgNPWmSN+WHq205nPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}