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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0acd724b6bc5848a07ae367af41ca07425a08145931c6f9f3fe7c4010b6f7804' 
  AND token = 'Lk5VHJ1TZg505vESa0XrF3JKIfFlYK2aQCHsPgMJ2/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}