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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '850c120cc7c0d06c4261962c14151616abc6a0c88db2a2587afc3bc0dc8bf3b2' 
  AND token = 'D4kuLFt+SD0J3tE2adUxyQlPMmSS3XBJVqKw2athDVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}