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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee17be63f3d4f2ef79f2662321336ee204c13673a698446ce2b5aa9c66249191' 
  AND token = 'FVg0Sc4uu+BIU+Bb7PDuYrbgcQgVNVf2N0Cw1Hcx1pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}