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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b73eaaf0734ea4bc4019c1926f758ed93eb361a9d520d04b98f9021330d444d8' 
  AND token = 'NK11yu7GbBLyjXuWUGmNrh2GJ1iKcu0fJchiun+HAMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}