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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72eaa855879e27eea31bcf381df7847a5cd0732d88bdd5be020205a8006dae8' 
  AND token = '7SmdTTJ8IO9o3haivcJ7B02gigt1iehN54PzDR1kq9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}