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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e61ffb13d0cd774ab2ece75bbfbed46e83028a9f18f1c2a6511b46b8e3d0fb' 
  AND token = '5xFmSwloI/1tZLHzWER+zWSTCo5hed8QRu6Pa4QzJwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}