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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8d3081927a4931e52236621f15abd44911e7b7344c131d6b84aec3ed5a3689' 
  AND token = 'wwCgn7GjmcRgkK8n9okYZeZMEKC5XtEOBglN8DZUxh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}