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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06c75f017e9eb9afdb8e2c2a6dc72bae0217b684cb2a1f4385977f85f8eab9a3' 
  AND token = 'OSSoAOzjpj+hL2ELuk+Wc5Tqfs4EgSbniU8gD7StHzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}