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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '897c611f7eaf9572bd6b4444df87a21993fc25f0f4dea6808274166af146cdfc' 
  AND token = 'Wo2Eh1ndcIwL2w8GbJWtS93HzUz8eAh3eNDjKmA/C5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}