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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c09e1b95a366b406f341e7667b468e9b7a7afbc631cebe06d1daca22bb315d28' 
  AND token = 'gMAYPy9K8MYvRxxy2jLS5v7sD4GNK4tNV9aqqNM44r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}