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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51201435c52070c44d16a2236e6eb56b138334079b31e633e866b90eb2ae0cbe' 
  AND token = 'Hvu4gUELxz9ZWyvqKdmWMZMlLBrIykuZw6FzyJqgy7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}