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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1001dcabda6802fd1d96d49fa871c84b9a3a9ba6754d97dc784a1aa54f6f68' 
  AND token = 'MDfNolL4hkwx5g9wgsQTD3Eb2kmubOSPC2r9EJbpL7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}