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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7748a61de6ec2cf088467296ce0f1d2a8a2c7d99bbb367b246a1206a4002f18' 
  AND token = 'Rm34MmxV9/9P3bvXMXvgr/HDD5FGzbbfj6qzLiw7OKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}