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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3830235b458a27bbd84767d96c74bd869f941bc4892de9dced4c9cae48b333' 
  AND token = '0k4i4C9e+INPaT7kjF2PsceDZyiwfhWODPZ0W0IcmR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}