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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051aa5ba34bf66ef240a1467fc9f39eb2d1e5ea04337a3fc36241a0af7a749d8' 
  AND token = 'Ys6NVF19L42kVaDjTpxmrQfTMwA+NXLOOLFW4QcdJWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}