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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2440045023e8594b815a12303af467aa8e852a8cbdd0405a5ec7a933d27af4' 
  AND token = 'E9tzAvbQ9W9BV9GVwoX0gHDX2Dx9Rqd/7wIDPqCvoaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}