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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f6ebd55df5e0cb57b3853710f410526cf80fb83b1f9de449ee8d954d644530' 
  AND token = 'zBC6ePM0OkgySwUsaqPWsUNjD0S5rgMdV06f/HRw3Z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}