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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f19218d8449a7d96d591dcbab0d65749adb7e57f5701bc6425a5c5b166f13b67' 
  AND token = 'qLVINMBW2CPEKjWZ/5NHdC0T7NJ8WRSmodL6iyaOKL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}