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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08103b3825efc7d8f34ca546a203844a0b3b133b41ff2fc622dbc9f6d1b1a640' 
  AND token = 'R2cvkSo0Qx8ezrlGn9d6bgcvVw6QxYCdmcmjiKXHmXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}