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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f18354e653bf7876cb19ceb6ea2e9b95bfc0e32ade2974e55474acd7f663241' 
  AND token = 'y3Kbfswc5k2yc7lGXmRpX3Adci5aXgU/4HZ4Pp3xJ+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}