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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea22b707af4a05162129ac4af84899273d3c6b601d074da201f9d3e5f9ed5e1' 
  AND token = '0qAiSfZpJgodBR0HA3E9/PCPwSzAa52mJ5+kBXOetBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}