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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd88ff415ffe1e9f2c17060f966de13d832d7f06f4aef3d9d20b832c1ec8127' 
  AND token = 'VZzAUq3MdGAMo03FhRH/2QFcCHLsy5e9/LtzHdHrCiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}