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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea2c9361cb42c6f25d11f249af307a4cca2575db5da90208ba9f2de93aa3089' 
  AND token = 'LbRv1EI5CaCp2wbCX++FRPmFpk01KonaMgW5R9xlchI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}