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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe7815f4ea158141016db94f83fdb69b612e51649b45a8ba26c0cd7b97033797' 
  AND token = 'jzdE1qoMM8BVcjFTbEQI5CFSsuWBHXlam2k67arW3CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}